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# Scientific publication credits performance of Carbios’ PET degradation enzyme for bio-recycling
- URL: https://www.packagingeurope.com/scientific-publication-credits-performance-of-carbios-pet-degradation-enzyme-for-bio-recycling/
- Published: 2023-10-12T09:50:00.000Z
- Updated: 2025-05-22T21:10:43.000Z
- Author: Packaging Europe staff writers
- Tags: Sustainability, #layout-s, #type-article, #packaging-europe, #Import 2026-09-08 15:47

[**Carbios**](https://www.carbios.com/en/?ref=packagingeurope.com)**’ enzyme for degrading PET has beenreportedas the best-performing under industrial conditions in a new scientific publication, and it is set to be used for depolymerization in the ‘world’s first’ bio-recycling plant due for commissioning in 2025.**

Scientific journal [ACS Catalysis](https://pubs.acs.org/journal/accacs?ref=packagingeurope.com) has published an [article](https://pubs.acs.org/doi/epdf/10.1021/acscatal.3c02922?ref=packagingeurope.com) titled ‘Assessment of Four Engineered PET Degrading Enzymes Considering Large-Scale Industrial Applications’. It compares two variants of the IsPETase enzyme produced by *Ideonella sakaiensis* from the [University of Manchester](https://www.manchester.ac.uk/?ref=packagingeurope.com) and the [University of Texas at Austin](https://www.utexas.edu/?ref=packagingeurope.com); a variant of PES-H1, also known as PHL7, from the [University of Greifswald](https://www.uni-greifswald.de/en/?ref=packagingeurope.com); and Carbios’ LCCICCG enzyme – claiming that the latter outperforms all its competitors.

Reportedly, Carbios and [Toulouse Biotechnology Institute](https://www.toulouse-biotechnology-institute.fr/en/?ref=packagingeurope.com) have used a standardized method to compare PET degrading enzymes under industrial conditions and concluded that LCCICCG offers ‘superior performance’. Its capabilities have apparently been optimized since its original publication in [Nature](https://www.nature.com/?ref=packagingeurope.com)in 2020, and although its newest results have not yet been published, the enzyme is projected for use in its upcoming bio-recycling plant.

“With this publication in the prestigious ACS Catalysis journal, we wanted to offer the scientific community a standardized method for comparing enzymes under industrial conditions,” said Alain Marty, chief scientific officer at Carbios. “This study confirms Carbios’ position as a leader not only for the superior performance of its enzyme for the degradation of PET, but above all in its industrial-scale application for the biorecycling of plastic and textiles.

“I would like to thank all my teams and my fellow co-authors for their collaboration and perseverance in publishing this landmark article.”

Enzymologists Professor Uwe Bornscheuer from the University of Greifswald and Professor Gert Weber from [Helmholtz-Zentrum Berlin](https://www.helmholtz-berlin.de/?ref=packagingeurope.com) are credited as collaborators in Carbios’ pursuit of biological recycling for PET. Carbios has also proposed an international standardized method for enzyme comparison, a move that it believes to establish its position as ‘the world leader of enzymatic PET depolymerization’.

Back in 2021, Carbios opened an [industrial demonstration plant](https://packagingeurope.com/carbios-launches-industrial-demonstration-plant-for-its-enzymatic-recycling-technology/1915.article?ref=packagingeurope.com) as part of the commercialisation of its C-ZYME enzymatic recycling technology. Soon after, it collaborated with [Indorama Ventures](https://www.indoramaventures.com/en/home?ref=packagingeurope.com) to plan for a [manufacturing plant](https://packagingeurope.com/news/carbios-and-indorama-ventures-to-build-first-of-its-kind-manufacturing-plant-for-bio-recycled-pet/7913.article?ref=packagingeurope.com) at the latter’s PET production site in France.

Scientists from [Leipzig University](https://www.uni-leipzig.de/en?ref=packagingeurope.com) also discovered an enzyme thought to [degrade PET in record time](https://packagingeurope.com/features/can-pet-eating-enzymes-help-to-solve-the-plastic-waste-problem/8431.article?ref=packagingeurope.com), and project leader Dr Christian Sonnendecker talked Packaging Europe through this development.

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